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Updated: Jul 16, 2025

Synthesis of Information-bearing Peptoids and their Sequence-directed Dynamic Covalent Self-assembly
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同期マクロサイクル形成によるナヤアミンCの総合成

Thomas Varlet1, Sören Portmann1, Alois Fürstner1

  • 1Max-Planck-Institut für Kohlenforschung, 45470 Mülheim/Ruhr, Germany.

Journal of the American Chemical Society
|September 21, 2023
PubMed
まとめ

研究者らは,新しい二重環閉アルキンメタテシス (dRCAM) 戦略を用いて,海洋天然産物であるニャオアミンCの最初の完全合成を達成しました. この革新的な方法は,複雑なマクロサイクル構造を効率的に構築し,アルカロイド合成を進めます.

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