関連する実験動画

Updated: Jul 16, 2025

Live Imaging and Quantification of Viral Infection in K18 hACE2 Transgenic Mice Using Reporter-Expressing Recombinant SARS-CoV-2
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Live Imaging and Quantification of Viral Infection in K18 hACE2 Transgenic Mice Using Reporter-Expressing Recombinant SARS-CoV-2

Published on: November 5, 2021

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SARS-CoV-2の変種は,宿主反応を再構築するためのコンバージェント戦略を進化させる

Mehdi Bouhaddou1, Ann-Kathrin Reuschl2, Benjamin J Polacco3

  • 1Quantitative Biosciences Institute (QBI), University of California, San Francisco, San Francisco, CA, USA; QBI Coronavirus Research Group (QCRG), University of California, San Francisco, San Francisco, CA, USA; Department of Microbiology, Immunology, and Molecular Genetics (MIMG), University of California, Los Angeles, Los Angeles, CA, USA; Institute for Quantitative and Computational Biosciences (QCBio), University of California, Los Angeles, Los Angeles, CA, USA; Molecular Biology Institute, University of California, Los Angeles, Los Angeles, CA, USA.

Cell
|September 22, 2023
PubMed
まとめ

SARS-CoV-2の変種は,ウイルスおよび宿主因子を変化させ,宿主免疫を回避するための類似の戦略を進化させた. オミクロンサブバリエーションは免疫反応を抑制する上で様々な成功を収め,進行中のウイルス進化を強調した.

キーワード:
SARS-CoV-2について生まれつきの免疫タンパク質とタンパク質の相互作用プロテオミクスシステム生物学トランスクリプトミクスバリアントウイルスと宿主の相互作用

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