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Updated: Jul 15, 2025

Development of a Backbone Cyclic Peptide Library as Potential Antiparasitic Therapeutics Using Microwave Irradiation
08:48

Development of a Backbone Cyclic Peptide Library as Potential Antiparasitic Therapeutics Using Microwave Irradiation

Published on: January 26, 2016

11.9K

サイトクロームP450マクロサイクラゼによって生成されるビアリルを含むペプチドの多様な風景を探索

Hyunsung Nam, Joon Soo An, Jaepil Lee

    Journal of the American Chemical Society
    |September 27, 2023
    PubMed
    まとめ

    サイトクロームP450酵素は,リボソーム合成および翻訳後の改変ペプチド (RiPP) で多様なビアリル結合を作り,これらの天然製品の化学的多様性を拡大します. この研究では,新しいP450マクロサイクラスを特定し,シプチドと呼ばれる新しいビアリルを含むペプチドを特徴付けました.

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