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Updated: Jul 15, 2025

Preparation of Enantiopure Non-Activated Aziridines and Synthesis of Biemamide B, D, and epiallo-Isomuscarine
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Preparation of Enantiopure Non-Activated Aziridines and Synthesis of Biemamide B, D, and epiallo-Isomuscarine

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(-) - カウラミジンDと (-) - アイソカウラミジンDのエナンチオセレクティブ・トータル・シンセシスと,それらの絶対的構成の再配置

Haiyong Yu1, Junhao Zhang1, Dongxu Ma1

  • 1Molecular Synthesis Center and Key Laboratory of Marine Drugs, MOE, and School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, China.

Journal of the American Chemical Society
|October 4, 2023
PubMed
まとめ

最初のエナチオセレクティブの (-) - カウラミジンDと (-) - アイソカウラミジンDの総合成は,統一された16段階の戦略を用いて達成された. 主な反応には,非対称的な再配置とカスケードサイクルが含まれ,それらのTFA塩の形態が確認されました.

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