関連する実験動画

Updated: Jul 15, 2025

Identifying PD-1/PD-L1 Inhibitors with Surface Plasmon Resonance Technology
07:04

Identifying PD-1/PD-L1 Inhibitors with Surface Plasmon Resonance Technology

Published on: May 2, 2025

393

PTPN2/PTPN1阻害剤 ABBV-CLS-484は強力な抗腫瘍免疫を放出する

Christina K Baumgartner1, Hakimeh Ebrahimi-Nik2,3,4, Arvin Iracheta-Vellve2,3,5

  • 1AbbVie, North Chicago, IL, USA. christina.baumgartner@abbvie.com.

Nature
|October 4, 2023
PubMed
まとめ

新しい薬であるABBV-CLS-484 (AC484) は,抗腫瘍免疫を強化するために,タンパク質チロシンファスファターゼPTPN2とPTPN1を標的とする. この経口投与可能な阻害剤は,現在のがん免疫療法に対する耐性を克服する有望な結果を示しています.

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