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Updated: Jul 14, 2025

Monitoring Equilibrium Changes in RNA Structure by 'Peroxidative' and 'Oxidative' Hydroxyl Radical Footprinting
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リボヌクレオチド還元酵素R2タンパク質の構造

Hugo Lebrette1,2, Vivek Srinivas1, Juliane John1

  • 1Department of Biochemistry and Biophysics, Stockholm University, Arrhenius Laboratories for Natural Sciences, Stockholm, Sweden.

Science (New York, N.Y.)
|October 5, 2023
PubMed
まとめ

アエロビックリボヌクレオチド還元酵素 (RNRs) は,R2で DNA を生成する根幹を生成する. 新しい構造は,RNRが,プロトン結合電子移転 (PCET) 経由でDNA合成のためにこのラジカルをシールドし,移動させる方法を示しています.

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