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Updated: Jul 13, 2025

Generating Recombinant Avian Herpesvirus Vectors with CRISPR/Cas9 Gene Editing
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CRISPR で 編集 さ れ た ニワトリ が インフルエンザ を 避ける の は"概念 の 証明" で ある

Jon Cohen

    Science (New York, N.Y.)
    |October 12, 2023
    PubMed
    まとめ

    遺伝子編集は感染制御の可能性を秘めているが,単一の遺伝子を改変しても感染を完全に止めるには不十分である. 病原体に対する包括的な遺伝的戦略を探るにはさらなる研究が必要である.

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    Genome editing technologies allow scientists to modify an organism’s DNA via the addition, removal, or rearrangement of genetic material at specific genomic locations. These types of techniques could potentially be used to cure genetic disorders such as hemophilia and sickle cell anemia. One popular and widely used DNA-editing research tool that could lead to safe and effective cures for genetic disorders is the CRISPR-Cas9 system. CRISPR-Cas9 stands for Clustered Regularly Interspaced...
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    The CRISPR-Cas system serves as a bacterial defense mechanism against invading genetic elements such as viruses and plasmids, forming the foundation for its adaptation as a powerful genome-editing tool. Originally discovered in prokaryotes, this system has been repurposed to revolutionize genetic engineering across a wide range of organisms, including plants, animals, and humans. The core component, Cas9, is an endonuclease derived from Streptococcus pyogenes, capable of introducing...
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