甲状腺 機能 障害: 概要
Sun Y Lee1, Elizabeth N Pearce1
1Section of Endocrinology, Diabetes, Nutrition, and Weight Management, Boston University Chobanian and Avedisian School of Medicine, Boston, Massachusetts.
JAMA
|October 17, 2023
まとめ
高甲状腺症は 成人の2.5%に影響し 心臓病や骨粗鬆症などの深刻な健康問題を引き起こします 早期診断と 抗甲状腺薬,手術,放射性ヨウ素を含む 個別的な治療は,この状態の管理に極めて重要です.
科学分野:
- 内分泌学
- 内科 医学
背景:
- 過剰な甲状腺症 (低チロトロピン,高T3/FT4) は,世界全体で0. 2~1. 4%に罹患する.
- サブクリニック性甲状腺症 (低チロトロピン,正常のT3/FT4) は,世界全体で0. 7~1. 4%に罹患する.
- 治療されていない甲状腺症は死亡リスクを高め,心律不整,心不全,骨粗鬆症を引き起こす可能性があります.
研究 の 目的:
- 甲状腺機能過剰症の流行,原因,症状,治療について見直す.
- 患者中心の治療方法の重要性を強調する
主な方法:
- 診断のための臨床表現,甲状腺機能検査,およびチロトロピン受容体抗体の状態のレビュー.
- 甲状腺のシンチグラフィーを検討し,原因や結節の有無を明らかにする.
- 抗甲状腺薬,放射性ヨウ素除去,手術などの治療法の評価
主要な成果:
- グレヴス病は最も一般的な原因である (女性では2%,男性では0.5%).
- 症状には,不安,不眠,心拍,体重減少が含まれます. グラブス病は,または外視で現れる可能性があります.
- 毒性結節は圧縮症状を引き起こし,甲状腺炎はサポート的に管理することができます.
結論:
- 甲状腺機能不全は世界中の成人の2.5%に影響し,骨粗鬆症,心臓病,死亡率に関連しています.
- 抗甲状腺薬,手術,放射性ヨウ素などの治療法があります.
- 患者中心の個別化された治療は 最適な結果を得るために不可欠です
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