治療目的のオリゴヌクレオチドを設計するためのRNA/DNAハイブリッド複合体の細胞内安定性予測

Dipanwita Banerjee1, Hisae Tateishi-Karimata1, Maria Toplishek2

  • 1Frontier Institute for Biomolecular Engineering Research (FIBER), Konan University, 7-1-20 minatojima-Minamimachi, Chuo-ku, Kobe 650-0047, Japan.

まとめ

細胞内の分子の混雑は RNA/DNAハイブリッド複合体を不安定にします 新しいパラメータは二重の安定性を予測し,遺伝子調節と核酸治療を助けます.

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