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Updated: Jul 12, 2025

Author Spotlight: Characterizing Novel Enzymes from Extremophiles and Common Pathogens to Understand DNA Repair and Replication
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Author Spotlight: Characterizing Novel Enzymes from Extremophiles and Common Pathogens to Understand DNA Repair and Replication

Published on: July 5, 2024

698

三価稀土金属コファクターは,急速なNP-DNAポリメラーゼ活性を与える

Victor S Lelyveld1,2, Ziyuan Fang1,2,3, Jack W Szostak1,2,3,4,5,6

  • 1Center for Computational and Integrative Biology, Department of Molecular Biology, Massachusetts General Hospital, Boston, MA 02114, USA.

Science (New York, N.Y.)
|October 26, 2023
PubMed
まとめ

研究者は,優れた金属イオンコファクターを特定することによって,非自然なN3'→P5'フォスフォラミダート (NP) のDNA合成を強化しました. スカンジウム (III) は,標準的なカルシウム (II) コーファクターと比較して,NP-DNA形成を著しく促進する.

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