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Updated: Jul 12, 2025

Glycopeptide Capture for Cell Surface Proteomics
10:11

Glycopeptide Capture for Cell Surface Proteomics

Published on: May 9, 2014

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コンフォーマル・リストリクトド・グリコペプチド・バックボーンは,グリカンとペプチド・モイエティの間のガス相H/Dスクランブルを阻害する

Christian Code1,2, Danwen Qiu1, Ilia A Solov'yov2,3,4,5

  • 1Department of Pharmacy, Faculty of Health and Medical Sciences, University of Copenhagen, 2100 Copenhagen, Denmark.

Journal of the American Chemical Society
|October 26, 2023
PubMed
まとめ

グリコペプチドの衝突誘発解離 (CID) は,グリカンデウテリウム含有量を明らかにすることができます. しかし,断片化中の水素/デウテリウム (H/D) の混同は,バンコミシンのような形状的に制限された分子とは異なり,ほとんどのグリコプロテインの正確な分析を妨げます.

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