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Updated: May 7, 2026

Isolation of Cortical Microglia with Preserved Immunophenotype and Functionality From Murine Neonates
09:12

Isolation of Cortical Microglia with Preserved Immunophenotype and Functionality From Murine Neonates

Published on: January 30, 2014

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iPS細胞由来マイクログリアは,コレステロールの移転を通じて脳オルガノイドの成熟を促進する

Dong Shin Park1,2, Tatsuya Kozaki1, Satish Kumar Tiwari1

  • 1Singapore Immunology Network (SIgN), Agency for Science, Technology and Research, Singapore, Singapore.

Nature
|November 2, 2023
PubMed
まとめ

研究者は原始的なマクロファージを加えることで 微小細胞に十分な脳オーガノイドを開発しました これらのエンジニアリングされたマイクログリア (iMicro) はニューロンの発達を調節し,脂質輸送を通じて軸索の成長を促し,脳のオルガノイドモデルを前進させます.

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