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Updated: Jul 12, 2025

Structure and Coordination Determination of Peptide-metal Complexes Using 1D and 2D 1H NMR
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Structure and Coordination Determination of Peptide-metal Complexes Using 1D and 2D 1H NMR

Published on: December 16, 2013

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コバルト-硫黄調整化学 B12メチオニン合成への負荷

Romila Mascarenhas1, Arkajit Guha1, Zhu Li1

  • 1Department of Biological Chemistry, University of Michigan, Ann Arbor, Michigan 48109, United States.

Journal of the American Chemical Society
|November 2, 2023
PubMed
まとめ

人間のコバラミン密輸タンパク質MMADHCは,不活性なコバルト-硫黄結合を使用して,ビタミンB12をメチオニン合成体に転送します. このメカニズムは,MMADHC変異の患者におけるホモシスティヌリアを説明します.

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