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関連する概念動画

Maxam-Gilbert Sequencing01:05

Maxam-Gilbert Sequencing

11.2K
In the same year as the discovery of the Sanger sequencing method, another group of scientists, Allan Maxam and Walter Gilbert, demonstrated their chemical-cleavage method for DNA sequencing. The Maxam-Gilbert method relies on using different chemicals that can cleave the DNA sequence at specific sites, the separation of resulting DNA fragments of variable size using electrophoresis, and deciphering the DNA sequence from the resulting gel bands.
Challenges of the Maxam-Gilbert Method
The...
11.2K
Next-generation Sequencing03:00

Next-generation Sequencing

89.0K
The first human genome sequencing project cost $2.7 billion and was declared complete in 2003, after 15 years of international cooperation and collaboration between several research teams and funding agencies. Today, with the advent of next-generation sequencing technologies, the cost and time of sequencing a human genome have dropped over 100 fold.
Next-Generation Sequencing Methods
Although all next-generation methods use different technologies, they all share a set of standard features....
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Multi-species Conserved Sequences02:51

Multi-species Conserved Sequences

3.9K
Next-generation sequencing technologies have created large genomic databases of a variety of animals and plants. Ever since the human genome project was completed, scientists studied the genome of primates, mammals, and other phylogenetically distant living beings. Such large-scale  studies have provided new insights into the evolutionary relationship between organisms.
Although the genome of each species varies greatly from each other, a few sequences are highly conserved. Such conserved...
3.9K
Sanger Sequencing01:57

Sanger Sequencing

754.6K
DNA sequencing is a fundamental technique that is routinely used in the biological sciences. This method can be applied to a range of questions at different scales - from the sequencing of a cloned DNA fragment or the study of a mutation in a gene up to whole-genome sequencing. However, despite the widespread use of sequencing today, it was not until 1977 that Fredrick Sanger and his collaborators developed the chain-termination method to decode DNA sequences. It relies on the separation of a...
754.6K
RNA-seq03:21

RNA-seq

10.0K
RNA sequencing, or RNA-Seq, is a high-throughput sequencing technology used to study the transcriptome of a cell. Transcriptomics helps to interpret the functional elements of a genome and identify the molecular constituents of an organism. Additionally, it also helps in understanding the development of an organism and the occurrence of diseases. 
Before the discovery of RNA-seq, microarray-based methods and Sanger sequencing were used for transcriptome analysis. However, while...
10.0K
Evolutionary Relationships through Genome Comparisons02:54

Evolutionary Relationships through Genome Comparisons

5.8K
Genome comparison is one of the excellent ways to interpret the evolutionary relationships between organisms. The basic principle of genome comparison is that if two species share a common feature, it is likely encoded by the DNA sequence conserved between both species. The advent of genome sequencing technologies in the late 20th century enabled scientists to understand the concept of conservation of domains between species and helped them to deduce evolutionary relationships across diverse...
5.8K

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関連する実験動画

Updated: Jul 11, 2025

Detection of Rare Genomic Variants from Pooled Sequencing Using SPLINTER
14:06

Detection of Rare Genomic Variants from Pooled Sequencing Using SPLINTER

Published on: June 23, 2012

15.3K

デジタルシーケンス情報における新たな利益分担の原則

Michael Halewood1, Margo A Bagley2, Markus Wyss3

  • 1Alliance of Bioversity International and the International Center for Tropical Agriculture, Rome, Italy.

Science (New York, N.Y.)
|November 2, 2023
PubMed
まとめ
この要約は機械生成です。

利益分担協定はアクセスプロトコルから分離する必要があります. これは資源の公平な分配を保証し,研究開発における利益の衝突を防止します.

さらに関連する動画

Novel Sequence Discovery by Subtractive Genomics
09:40

Novel Sequence Discovery by Subtractive Genomics

Published on: January 25, 2019

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High-throughput Identification of Gene Regulatory Sequences Using Next-generation Sequencing of Circular Chromosome Conformation Capture 4C-seq
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High-throughput Identification of Gene Regulatory Sequences Using Next-generation Sequencing of Circular Chromosome Conformation Capture 4C-seq

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関連する実験動画

Last Updated: Jul 11, 2025

Detection of Rare Genomic Variants from Pooled Sequencing Using SPLINTER
14:06

Detection of Rare Genomic Variants from Pooled Sequencing Using SPLINTER

Published on: June 23, 2012

15.3K
Novel Sequence Discovery by Subtractive Genomics
09:40

Novel Sequence Discovery by Subtractive Genomics

Published on: January 25, 2019

8.7K
High-throughput Identification of Gene Regulatory Sequences Using Next-generation Sequencing of Circular Chromosome Conformation Capture 4C-seq
09:06

High-throughput Identification of Gene Regulatory Sequences Using Next-generation Sequencing of Circular Chromosome Conformation Capture 4C-seq

Published on: October 5, 2018

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科学分野:

  • バイオテクノロジー
  • 環境科学
  • 公衆衛生

背景:

  • 生物資源へのアクセスは科学の進歩にとって極めて重要です.
  • 利益分担のメカニズムは,資源利用から生じる利点の公平な分配を保証することを目的としています.
  • 現在の枠組みでは,利益の共有が直接アクセスに結びつけられ,複雑さを生み出しています.

研究 の 目的:

  • 生物資源の観点から アクセスと利益共有 (ABS) の関係を批判的に評価する.
  • 利益の共有がアクセスから切り離されるモデルを提案する.
  • 国際法と倫理的な観点から,このような分離がもたらす影響について検討する.

主な方法:

  • 既存のABSフレームワークと協定の文献レビュー
  • 資源へのアクセスと利益の共有に関するケーススタディの分析
  • 解き放たれたABSシステムの概念モデリング.

主要な成果:

  • 利益の共有とアクセスを直接結びつけることは 研究と公平な成果を妨げる可能性があります
  • 分離により,より柔軟で文脈特有の利益分担の取り決めが可能になります.
  • 分離されたモデルは,事前の知見による同意と伝統的な知識の問題に よりうまく対処できます.

結論:

  • 利益の共有とアクセスの分離は,真の公平性を達成するために不可欠です.
  • 解き放たれたABSフレームワークは より大きな協力とイノベーションを促すことができます
  • この分離を効果的に実施するには 政策と法的改革が必要である.