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Updated: Jul 11, 2025

Murine Model for Parkinson's Disease: from 6-OH Dopamine Lesion to Behavioral Test
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Published on: January 15, 2010

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循環特異遺伝子治療は,霊長類のパーキンソン病のモデルにおける主要な症状を逆転させる

Yefei Chen1, Zexuan Hong2, Jingyi Wang3

  • 1Shenzhen Technological Research Center for Primate Translational Medicine, Shenzhen Key Laboratory for Molecular Biology of Neural Development, Shenzhen-Hong Kong Institute of Brain Science, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China.

Cell
|November 3, 2023
PubMed
まとめ

この研究は,パーキンソン病 (PD) に対して特定の脳細胞を標的とした新しい遺伝子治療法を導入しています. このアプローチは動物モデルで 運動機能を回復し PDの症状に対する新たな治療法となる可能性があります

キーワード:
パーキンソン病化学遺伝学遺伝子療法人間以外の霊長類逆行するAAVターゲティング回路操作

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