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Updated: Jul 11, 2025

Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones
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Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones

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イリジウムアシルニートレノイドによるバイオミメティックカスケードサイクライゼーション:ポリサイクリック δ-ラクトームへのステレオ定義されたアクセス

Eleonora Tufano1, Euijae Lee2,3, Matteo Barilli1

  • 1Department of Chemistry, University of Pavia, Viale Taramelli 12, 27100 Pavia, Italy.

Journal of the American Chemical Society
|November 6, 2023
PubMed
まとめ

研究者は,リング融合アザサイクルの合成のための新しいバイオミメティックカスケードサイクライゼーションを開発しました. この効率的な方法は,アリアルケニルダイオクサゾロンを利用し,複雑な分子を作るための幅広い基板範囲と高いステレオ選択性を提供します.

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