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Updated: Jul 11, 2025

Synthesis of a Borylated Ibuprofen Derivative Through Suzuki Cross-Coupling and Alkene Boracarboxylation Reactions
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Synthesis of a Borylated Ibuprofen Derivative Through Suzuki Cross-Coupling and Alkene Boracarboxylation Reactions

Published on: November 30, 2022

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アリル塩化物誘導のエナチオセレクティブC ((sp2) -Hボリレーション

Hongliang Zhao1,2, Chao-Yue Zhao3, Lili Chen1

  • 1State Key Laboratory for Oxo Synthesis and Selective Oxidation, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou 730000, China.

Journal of the American Chemical Society
|November 7, 2023
PubMed
まとめ

この研究は,アリル塩化物のエナチオセレクティブC-Hボリレーションのためのイリジウム触媒法を導入し,高い選択性を持つ多様な軸性キラルビアリルを生み出します. 効率的な触媒システムは,非対称的なC−H活性化のための記録的なターンオーバー数 (TON) を達成した.

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