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Updated: Jul 11, 2025

High-throughput Quantitative Real-time RT-PCR Assay for Determining Expression Profiles of Types I and III Interferon Subtypes
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Published on: March 24, 2015

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代替NF-κB経路欠乏症の人におけるタイプIIFNに対する自己抗体

Tom Le Voyer1,2, Audrey V Parent3, Xian Liu3

  • 1Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM UMR1163, Paris, France. tom.le-voyer@institutimagine.org.

Nature
|November 8, 2023
PubMed
まとめ

NIK,RELB,またはNF-κB2の遺伝的欠乏は,I型インターフェロン (IFN) に対する自己抗体を生み出し,重度のCOVID-19のリスクを高めます. これはAPS-1とは異なり,胸膜AIRE細胞の発達を阻害する.

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