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Updated: Apr 30, 2026

Generation of iPSC-derived Human Brain Organoids to Model Early Neurodevelopmental Disorders
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単細胞脳オーガノイドスクリーニングは,自閉症の発達障害を特定します

Chong Li1, Jonas Simon Fleck2, Catarina Martins-Costa3

  • 1Institute of Molecular Biotechnology of the Austrian Academy of Science (IMBA), Vienna, Austria. chong.li@imba.oeaw.ac.at.

Nature
|November 14, 2023
PubMed
まとめ

No abstract available in PubMed .

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Neurulation01:30

Neurulation

Neurulation is the embryological process which forms the precursors of the central nervous system and occurs after gastrulation has established the three primary cell layers of the embryo: ectoderm, mesoderm, and endoderm. In humans, the majority of this system is formed via primary neurulation, in which the central portion of the ectoderm—originally appearing as a flat sheet of cells—folds upwards and inwards, sealing off to form a hollow neural tube. As development proceeds, the...
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