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Updated: Jul 11, 2025

Cultivate Primary Nasal Epithelial Cells from Children and Reprogram into Induced Pluripotent Stem Cells
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3Dエピジェネティックメモリシステムの設計原理

Jeremy A Owen1, Dino Osmanović2, Leonid Mirny1

  • 1Department of Physics, Massachusetts Institute of Technology, Cambridge, MA, USA.

Science (New York, N.Y.)
|November 16, 2023
PubMed
まとめ

細胞は3次元的なゲノム組織を通して 遺伝的記憶を維持します この構造はDNAの化学的変化を安定させ 細胞のアイデンティティを 世代から世代へと受け継がせます

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Epigenetics is the study of inherited changes in a cell's phenotype without changing the DNA sequences. It provides a form of memory for the differential gene expression pattern to maintain cell lineage, position-effect variegation, dosage compensation, and maintenance of chromatin structures such as telomeres and centromeres. For example, the structure and location of the centromere on chromosomes are epigenetically inherited. Its functionality is not dictated or ensured by the underlying...
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