関連する実験動画

Updated: Jul 10, 2025

Hi-C: A Method to Study the Three-dimensional Architecture of Genomes.
22:27

Hi-C: A Method to Study the Three-dimensional Architecture of Genomes.

Published on: May 6, 2010

409.1K

系統特有の3Dゲノム組織は,IKAROSによって複数のスケールで組み立てられています

Yeguang Hu1, Daniela Salgado Figueroa2, Zhihong Zhang1

  • 1Cutaneous Biology Research Center, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA.

Cell
|November 23, 2023
PubMed
まとめ

IKAROSタンパク質は,大規模なクロマチン相互作用をオーケストラし,CTCFの境界を覆し,細胞発達に不可欠な系統特有の規制単位を確立します. このクロマチンの再構成は 遺伝子発現を誘導し 細胞のアイデンティティを保証します

キーワード:
3Dゲノム組織Hi-C についてハイチップイカロスIgκロクスの収縮強化ループ区間間ループ系統特有のゲノム組織リンパ球の発達スーパーTAD

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