Jove
Visualize
お問い合わせ
JoVE
x logofacebook logolinkedin logoyoutube logo
JoVEについて
概要リーダーシップブログJoVEヘルプセンター
著者向け
出版プロセス編集委員会範囲と方針査読よくある質問投稿
図書館員向け
推薦の声購読アクセスリソース図書館諮問委員会よくある質問
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experimentsアーカイブ
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教員リソースセンター教員サイト
利用規約
プライバシーポリシー
ポリシー

関連する概念動画

Overview of Microscopy Techniques01:22

Overview of Microscopy Techniques

10.7K
The early pioneers of microscopy opened a window into the invisible world of microorganisms. In 1830, Joseph Jackson Lister created an essentially modern light microscope. The 20th century saw the development of microscopes that leveraged nonvisible light, such as fluorescence microscopy that uses an ultraviolet light source and electron microscopy that uses short-wavelength electron beams. These advances significantly improved magnification, image resolution, and contrast. By comparison, the...
10.7K
Two-Dimensional Microscopy in Microbiology01:29

Two-Dimensional Microscopy in Microbiology

1.8K
Two-dimensional (2D) microscopy encompasses a range of optical techniques that capture images within a single focal plane, offering detailed representations of microscopic structures. These techniques are essential in biological and medical research, enabling the visualization of cellular and subcellular structures with different levels of contrast and specificity.There are several major types of 2D microscopy, each with strengths and applications.Bright-Field MicroscopyBright-field microscopy...
1.8K
Three-Dimensional Microscopy in Microbiology01:28

Three-Dimensional Microscopy in Microbiology

907
Three-dimensional imaging techniques are essential in cell biology, allowing researchers to visualize intricate cellular structures with high resolution. Two prominent methods, Differential Interference Contrast Microscopy (DIC) and Confocal Scanning Laser Microscopy (CSLM), provide distinct advantages for imaging live and thick specimens, respectively.Differential Interference Contrast MicroscopyDIC microscopy enhances contrast in transparent, unstained samples by converting phase...
907

こちらも読む

関連記事

共著者、ジャーナル、引用グラフによってこの研究に関連する記事。

並び替え
Same author

Dynamic Self-Healing Polymer Architectures for High-Performance Flexible Sensing.

Advanced materials (Deerfield Beach, Fla.)·2026
Same author

Electrostatic asymmetry-assisted polarization enables tertiary amine anchoring in single-molecule junctions.

Chemical communications (Cambridge, England)·2026
Same author

Moisture-Gated Synergistic Rapid Crystal-to-Liquid Transition in Pyridinium Halide Crystals via [2 + 2] Photocycloaddition.

Small (Weinheim an der Bergstrasse, Germany)·2026
Same author

Diagnostic value of combined computed tomography lymphangiography and technetium-99m dextran lymphoscintigraphy in systemic lupus erythematosus complicated with chylous effusion and/or lymphedema.

Quantitative imaging in medicine and surgery·2026
Same author

Multi-stakeholder perspectives of palliative care needs in advanced COPD: a qualitative study.

BMC palliative care·2026
Same author

J-shaped relationship between stress hyperglycemia ratio and delirium risk in critically ill patients: A population-based study.

PloS one·2026

関連する実験動画

Updated: Apr 30, 2026

Fluorescence Lifetime Imaging of Molecular Rotors in Living Cells
09:45

Fluorescence Lifetime Imaging of Molecular Rotors in Living Cells

Published on: February 9, 2012

25.3K

バタフライ・モーションベースの光探査機を用いて,ミセルの内部における深度依存の微粘性を探求する

Xuanying Chen1, Shideng Yuan2, Mengyuan Qiao1

  • 1Key Laboratory for Advanced Materials and Feringa Nobel Prize Scientist Joint Research Center, Frontiers Science Center for Materiobiology and Dynamic Chemistry, School of Chemistry and Molecular Engineering, East China University of Science and Technology, Shanghai 200237, China.

Journal of the American Chemical Society
|November 24, 2023
PubMed
まとめ

研究者はミセルの内部の粘度を測定するために新しい光表面活性物質 (DPAC-Fn) を開発した. 彼らはミセル核から表面への有意な粘度変化を発見し,ミセル研究のための新しいツールを提供しました.

さらに関連する動画

Phase Behavior of Charged Vesicles Under Symmetric and Asymmetric Solution Conditions Monitored with Fluorescence Microscopy
10:08

Phase Behavior of Charged Vesicles Under Symmetric and Asymmetric Solution Conditions Monitored with Fluorescence Microscopy

Published on: October 24, 2017

9.2K
A Quantitative Fluorescence Microscopy-based Single Liposome Assay for Detecting the Compositional Inhomogeneity Between Individual Liposomes
09:12

A Quantitative Fluorescence Microscopy-based Single Liposome Assay for Detecting the Compositional Inhomogeneity Between Individual Liposomes

Published on: December 13, 2019

7.9K

関連する実験動画

Last Updated: Apr 30, 2026

Fluorescence Lifetime Imaging of Molecular Rotors in Living Cells
09:45

Fluorescence Lifetime Imaging of Molecular Rotors in Living Cells

Published on: February 9, 2012

25.3K
Phase Behavior of Charged Vesicles Under Symmetric and Asymmetric Solution Conditions Monitored with Fluorescence Microscopy
10:08

Phase Behavior of Charged Vesicles Under Symmetric and Asymmetric Solution Conditions Monitored with Fluorescence Microscopy

Published on: October 24, 2017

9.2K
A Quantitative Fluorescence Microscopy-based Single Liposome Assay for Detecting the Compositional Inhomogeneity Between Individual Liposomes
09:12

A Quantitative Fluorescence Microscopy-based Single Liposome Assay for Detecting the Compositional Inhomogeneity Between Individual Liposomes

Published on: December 13, 2019

7.9K

科学分野:

  • 超分子化学
  • 物理化学
  • 材料科学

背景:

  • 微小細胞の内部は複雑な粘度グラデーションを示し,実験的に測定することは困難です.
  • これらのグラデーションを理解することは,薬物投与と触媒の応用において極めて重要です.

研究 の 目的:

  • ミセル内の深度依存微微粘性を定量化するために新しい光表面活性物質を開発し,使用する.
  • 表面活性物質のアルキル鎖長とミセル内部の粘度との関係を調べる.

主な方法:

  • 粘度センサ (DPAC) でアルキルトリメチルアモニウムブロミドを機能化することによって,フローロホルム置換表面活性物質 (DPAC-Fn) の合成.
  • DPAC-Fnの粘度に敏感な多色放射を活用してミセラ環境を調査する.
  • セトリモニウムブロミド (CTAB) のミセル内の定量的粘度測定のための外部標準を使用する.

主要な成果:

  • CTABミセルにおけるDPAC-Fnの浸入深さは,アルキル鎖の長さ (n) に応じて変化した.
  • 効率的で粘度に敏感な多色放射が観察され,浸水深さと相関していた.
  • ~4 nmのCTABミセル内に ~190 Pa·sから ~1 Pa·sまでの有意な粘度グラデントが定量化されました.

結論:

  • 開発されたDPAC-Fn表面活性剤は,ミセラ内部の微小粘度を探索するための強力なツールとして機能します.
  • この研究は,ミセルの中心から表面までの劇的な粘度変化を実験的に確認し,定量化しています.
  • これは,深層のミセラー特徴化のためのカスタマイズされたアプローチを提供します.