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Updated: Jul 9, 2025

Sample Preparation and Analysis of RNASeq-based Gene Expression Data from Zebrafish
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MSL2は哺乳類のバイアレル遺伝子発現を保証する

Yidan Sun1, Meike Wiese1, Raed Hmadi1

  • 1Max Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany.

Nature
|November 29, 2023
PubMed
まとめ

MSL2タンパク質は哺乳類の遺伝子発現を調節し,重要な遺伝子の用量補償を保証する. MSL2の喪失は1つの遺伝子アレルの静止につながり,発達に影響を与え,マウスの死亡を引き起こします.

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Master Transcription Regulators

Master transcription regulators are regulatory proteins that are predominantly responsible for regulating the expression of multiple genes. Often these genes work in concert to drive a  complex process. Activation of a master transcription regulator can lead to a cascade of transcriptional activation necessary for that outcome. These regulators can directly bind to the regulatory sequences of the various genes involved, or they can indirectly regulate transcription by binding to regulatory...
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RNA Splicing

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Ribosome Profiling

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