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Updated: Jul 9, 2025

In Vitro Aggregation Assays Using Hyperphosphorylated Tau Protein
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In Vitro Aggregation Assays Using Hyperphosphorylated Tau Protein

Published on: January 2, 2015

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病気特有のタウ線維は,ポリモルフな中間体によって組み合わされる

Sofia Lövestam1, David Li1, Jane L Wagstaff1

  • 1MRC Laboratory of Molecular Biology, Cambridge, UK.

Nature
|November 29, 2023
PubMed
まとめ

研究者らはタウタンパク質の組み立てにおける 初期の中間アミロイドフィラメント構造を発見し アルツハイマー病のような 神経退行性疾患を理解し 新しい治療戦略を策定する上で 決定的な役割を果たしました

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