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Updated: Jul 9, 2025

Author Spotlight: Understanding DNA Damage Response in Mammalian Oocytes and Preimplantation Embryos
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Author Spotlight: Understanding DNA Damage Response in Mammalian Oocytes and Preimplantation Embryos

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ミオティックDNAの破裂は,ヒトの生殖系における多面的な変異を引き起こします

Robert Hinch1, Peter Donnelly2,3, Anjali Gupta Hinch2

  • 1Big Data Institute, University of Oxford, Oxford, UK.

Science (New York, N.Y.)
|November 30, 2023
PubMed
まとめ

精子再結合修復は高度に変異性があり,精子と卵子の新規変異を引き起こします. 予期せぬ誤りやすいDNA修復メカニズムは 遺伝的変化とヒトの生殖系における遺伝子破壊に寄与する.

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Mismatch Repair

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