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Constructing Cyclic Peptides Using an On-Tether Sulfonium Center
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Published on: September 28, 2022

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ネイティブペプチドサイクリング,水中の連続化学選択性アミデーション

Huan Chen1, Qiang Zhang1

  • 1Department of Chemistry, State University of New York, University at Albany, Albany, New York 12222, United States.

Journal of the American Chemical Society
|December 11, 2023
PubMed
まとめ

ネイティブ・ペプチド・サイクライゼーション (NPC) は,保護されていないペプチドの直接結合を可能にすることで,ペプチド合成を簡素化します. この新しい化学選択方法は,費用対効果の高い治療薬のための効率的な循環ペプチドの準備を容易にする.

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