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Updated: Jul 8, 2025

Author Spotlight: An Integrated Workflow to Study the Promoter-Centric Spatio-Temporal Genome Architecture in Scarce Cell Populations
11:36

Author Spotlight: An Integrated Workflow to Study the Promoter-Centric Spatio-Temporal Genome Architecture in Scarce Cell Populations

Published on: April 21, 2023

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スーパーエンハンスターは,遺伝子発現を完全に活性化するための古典的なエンハンスターとファシリテーターを含みます

Joseph W Blayney1, Helena Francis1, Alexandra Rampasekova1

  • 1MRC Weatherall Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, Headington, Oxford OX3 9DS, UK.

Cell
|December 15, 2023
PubMed
まとめ

スーパーエンハンスターは 遺伝子を活性化するために 異なる要素を使います ファシリテーター要素は古典的な強化剤を刺激し,細胞のアイデンティティに不可欠な強力な遺伝子活性化を保証します.

キーワード:
アルファ・グロービン・ロカスシス規制要素増強剤クラスター協力を強化するファシリテーター遺伝子発現ゲノム工学スーパーエンハンスター合成ゲノムトランスクリプション 規制

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