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Updated: Jul 8, 2025

Identification of Mediators of T-cell Receptor Signaling via the Screening of Chemical Inhibitor Libraries
08:49

Identification of Mediators of T-cell Receptor Signaling via the Screening of Chemical Inhibitor Libraries

Published on: January 22, 2019

9.2K

シグナルトランスデューサー CIN85 の自己抑制はB細胞の活性化を調節する

Daniel Sieme1, Michael Engelke2, Nasrollah Rezaei-Ghaleh3,4

  • 1Department for NMR-based Structural Biology, Max Planck Institute for Multidisciplinary Sciences, Am Fassberg 11, 37077 Göttingen, Germany.

Journal of the American Chemical Society
|December 19, 2023
PubMed
まとめ

新しく発見されたCIN85タンパク質の分子内相互作用は,B細胞受容体のシグナル伝達コンデンサートを調節する. この発見は,CIN85のバレンスの調節がB細胞の活性化とカルシウム動員にどのように影響するかを明らかにしています.

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