関連する実験動画

Updated: Jul 7, 2025

Advanced Imaging of Lung Homing Human Lymphocytes in an Experimental In Vivo Model of Allergic Inflammation Based on Light-sheet Microscopy
10:39

Advanced Imaging of Lung Homing Human Lymphocytes in an Experimental In Vivo Model of Allergic Inflammation Based on Light-sheet Microscopy

Published on: April 16, 2019

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センサリーニューロンは肺の免疫ホメオスタシスを促進する

Masato Tamari1, Kate L Del Bel2, Aaron M Ver Heul3

  • 1Kimberly and Eric J. Waldman Department of Dermatology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Mark Lebwohl Center for Neuroinflammation and Sensation, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Marc and Jennifer Lipschultz Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Department of Pediatrics, Jikei University School of Medicine, Minato-ku, Tokyo 1058471, Japan; Department of Allergy and Clinical Immunology, National Research Institute for Child Health and Development, Setagaya-ku, Tokyo 1578535, Japan.

Cell
|December 22, 2023
PubMed
まとめ

ジャヌスキナーゼ1 (JAK1) は,異なる組織で異なる役割を持っています. 感覚神経細胞では,JAK1は Calcb/CGRPβを調節することで,呼吸道炎症を抑制し,精密医療の新たな道を開きます.

キーワード:
AAV についてCGRP についてILC2 についてJAK1 についてアファレント神経アレルギー性肺炎アトピー症ニューロペプチド感覚神経細胞迷走神経

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