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Updated: Jul 6, 2025

Use of Ultra-high Field MRI in Small Rodent Models of Polycystic Kidney Disease for In Vivo Phenotyping and Drug Monitoring
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人間に遺伝するCCR2欠乏症は,進行性多囊性肺疾患の根底にある

Anna-Lena Neehus1, Brenna Carey2, Marija Landekic3

  • 1Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Necker Hospital for Sick Children, Paris 75015, France; Paris Cité University, Imagine Institute, Paris 75015, France.

Cell
|December 29, 2023
PubMed
まとめ

単細胞キモカイン受容体C-Cモチーフキモカイン受容体2 (CCR2) の完全な欠乏は,肺アルベオラタンパク質症および感染症を含むヒトの肺疾患を引き起こす. 高血C-Cモチーフリガンド2 (CCL-2) レベルは,この遺伝的状態を示す.

キーワード:
PAP についてケモタキシス閉塞性肺疾患マクロファージモノサイト再発性感染症

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