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Updated: Jul 6, 2025

Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones
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Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones

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多様な乳酸構造の酵素組成:分子内C-H機能化戦略

Daniel J Wackelin1, Runze Mao1, Kathleen M Sicinski1

  • 1Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125, United States.

Journal of the American Chemical Society
|January 2, 2024
PubMed
まとめ

科学者は新しいC-C結合戦略を通じて多様なラクトンを生成する新しい酵素であるカルベントランスファーゼを設計し,材料と医薬品のための自然の方法を補完しました.

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