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Updated: Jul 5, 2025

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Ptpn23は,ディストロフィン-グリコタンパク質複合体の組み立てを促進することによって,心臓T管のパターンを制御する

Chen Xu1,2,3, Ge Zhang1,2,3, Xinjian Wang1,2,3

  • 1Center for Genetic Medicine, The Fourth Affiliated Hospital (C.X., G.Z., X.W., X.H., J.Z., S.H., R.X., F.H., P.H.), Zhejiang University School of Medicine, Hangzhou, China.

Circulation
|January 12, 2024
PubMed
まとめ

非受容体型23型 (Ptpn23) のタンパク質チロシンフォスファタゼは,心臓のT管構造に不可欠です. Ptpn23の喪失はT管を壊し,拡張心筋病と心機能障害を引き起こす.

キーワード:
ディストロフィンTチューブル心筋病コスタメア

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