関連する実験動画

Updated: Jul 26, 2026

Understanding Early Organogenesis Using a Simplified In Situ Hybridization Protocol in Xenopus
14:50

Understanding Early Organogenesis Using a Simplified In Situ Hybridization Protocol in Xenopus

Published on: January 12, 2015

ヘパリン結合成長因子による早期のXenopus胚におけるメソデルマ誘導

J M Slack, B G Darlington, J K Heath

    Nature
    |March 12, 1987
    PubMed
    まとめ

    研究者らは,基礎線維芽細胞成長因子 (bFGF) を,両生類の初期胚発達における重要なシグナリング分子として特定した. この発見は,ボディプランを確立する上で極めて重要なベントロベゲタル (VV) 信号の化学的性質に光を当てています.

    さらに関連する動画

    Stem cell-like Xenopus Embryonic Explants to Study Early Neural Developmental Features In Vitro and In Vivo11:13

    Stem cell-like Xenopus Embryonic Explants to Study Early Neural Developmental Features In Vitro and In Vivo

    Published on: February 2, 2016

    Generation of Naïve Blastoderm Explants from Zebrafish Embryos07:21

    Generation of Naïve Blastoderm Explants from Zebrafish Embryos

    Published on: July 30, 2021

    関連する概念動画

    Determination01:51

    Determination

    During embryogenesis, cells become progressively committed to different fates through a two-step process: specification followed by determination. Specification is demonstrated by removing a segment of an early embryo, “neutrally” culturing the tissue in vitro—for example, in a petri dish with simple medium—and then observing the derivatives. If the cultured region gives rise to cell types that it would normally generate in the embryo, this means that it is specified. In contrast, determination...
    Regulation of Angiogenesis and Blood Supply01:24

    Regulation of Angiogenesis and Blood Supply

    Rapidly dividing tumors, embryos, and wounded tissues require more oxygen than usual, lowering the oxygen concentration in the blood. At low oxygen or hypoxic conditions, an oxygen-sensitive transcription factor called the hypoxia-inducible factor 1 or HIF1 is activated. HIF1 is a dimeric protein of alpha (ɑ) and beta (β) subunits.  Under optimal oxygen conditions, HIF1β is present in the nucleus while HIF1ɑ remains in the cytosol. HIF1ɑ is hydroxylated by prolyl hydroxylase and factor...
    Development of Blood Vessels01:07

    Development of Blood Vessels

    The development of the vascular system in a fetus is a complex and intricate process that begins as early as 15 to 16 days post-conception. This process starts outside the embryo, specifically in the mesoderm of the yolk sac, chorion, and connecting stalk. Approximately two days later, the formation of blood vessels occurs within the embryo itself.
    The initial formation of this system is facilitated by the small amount of yolk present in the ovum and yolk sac. Blood vessels originate from...