関連する実験動画

Updated: Jul 5, 2025

Constructing Thioether/Vinyl Sulfide-tethered Helical Peptides Via Photo-induced Thiol-ene/yne Hydrothiolation
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Constructing Thioether/Vinyl Sulfide-tethered Helical Peptides Via Photo-induced Thiol-ene/yne Hydrothiolation

Published on: August 1, 2018

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ピリジニウムの合理的な調節による無痕ペプチドとタンパク質の改変

Chuan Wan1,2, Yichi Zhang1, Jinpeng Wang1

  • 1State Key Laboratory of Chemical Oncogenomics, Guangdong Provincial Key Laboratory of Chemical Genomics, Peking University Shenzhen Graduate School, Shenzhen 518055, China.

Journal of the American Chemical Society
|January 19, 2024
PubMed
まとめ

痕跡のない システイン選択ペプチドと タンパク質の改変のための 新しいプラットフォームを開発しました この方法により,調整可能な結合と分裂が可能になり,抗体改変やプロテオームラベルなどの応用が可能になります.

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関連する概念動画

Covalently Linked Protein Regulators02:04

Covalently Linked Protein Regulators

Proteins can undergo many types of post-translational modifications, often in response to changes in their environment. These modifications play an important role in the function and stability of these proteins. Covalently linked molecules include functional groups, such as methyl, acetyl, and phosphate groups, and also small proteins, such as ubiquitin. There are around 200 different types of covalent regulators that have been identified.
These groups modify specific amino acids in a protein....
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