C-H

Eva Maria Alvarez1, Griffin Stewart1, Mohammed Ullah1

  • 1Department of Chemistry, Northwestern University, Technological Institute, Evanston, Illinois 60208, United States.

まとめ

新しい電気化学的方法により,二酸化炭素を中心とした二酸化炭素を用い,選択的な芳香性C-Hアミネーションが可能になる. この反応により,多様な機能群を許容する,高収量と地域選択性を持つアリルDABCOnium塩を形成する.

関連する概念動画

Thermal Electrocyclic Reactions: Stereochemistry01:17

Thermal Electrocyclic Reactions: Stereochemistry

The stereochemistry of electrocyclic reactions is strongly influenced by the orbital symmetry of the polyene HOMO. Under thermal conditions, the reaction proceeds via the ground-state HOMO.
Selection Rules: Thermal Activation
Conjugated systems containing an even number of π-electron pairs undergo a conrotatory ring closure. For example, thermal electrocyclization of (2E,4E)-2,4-hexadiene, a conjugated diene containing two π-electron pairs, gives trans-3,4-dimethylcyclobutene.
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Thermal and Photochemical Electrocyclic Reactions: Overview01:26

Thermal and Photochemical Electrocyclic Reactions: Overview

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Nucleophilic Aromatic Substitution: Elimination–Addition

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Regioselectivity of Electrophilic Additions to Alkenes: Markovnikov's Rule

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Amines to Alkenes: Hofmann Elimination01:16

Amines to Alkenes: Hofmann Elimination

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The rate of acid-catalyzed hydration of alkenes depends on the alkene's structure, as the presence of alkyl substituents at the double bond can significantly influence the rate.
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