関連する実験動画

Updated: Jul 4, 2025

Substrate Generation for Endonucleases of CRISPR/Cas Systems
11:53

Substrate Generation for Endonucleases of CRISPR/Cas Systems

Published on: September 8, 2012

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型III-B CRISPR-Cas タンパク質分裂のカスケード

Jurre A Steens1,2, Jack P K Bravo3, Carl Raymund P Salazar1

  • 1Laboratory of Microbiology, Wageningen University and Research, Wageningen, Netherlands.

Science (New York, N.Y.)
|February 1, 2024
PubMed
まとめ

タイプIIIのCRISPR-Casシステムは,タンパク質を活性化するために循環性オリゴアデニラートを生成します. この研究は,RNA検出がカスパースのようなプロテアースのカスケードを誘発し,ハリアンジウムオクラシウムにおける細菌の防御につながることを示しています.

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