関連する実験動画

Updated: Jul 4, 2025

Protein WISDOM: A Workbench for In silico De novo Design of BioMolecules
10:58

Protein WISDOM: A Workbench for In silico De novo Design of BioMolecules

Published on: July 25, 2013

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新しい構造からプログラム可能な機能へ

Tanja Kortemme1

  • 1Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, San Francisco, CA 94158, USA; Quantitative Biosciences Institute, University of California, San Francisco, San Francisco, CA 94158, USA; Chan Zuckerberg Biohub, San Francisco, CA 94158, USA.

Cell
|February 2, 2024
PubMed
まとめ

人工知能 (AI) は新しいタンパク質の設計を可能にし 特定の機能を持つ新しいタンパク質を生み出します このアプローチは,高度なタンパク質工学と合成生物学アプリケーションのための物理ベースのモデリングとAIを統合します.

キーワード:
人工知能de novo タンパク質のデザインディープラーニング合成信号

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Conservation of Protein Domains Over Different Proteins

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Proteins perform many mechanical functions in a cell. These proteins can be classified into two general categories- proteins that generate mechanical forces and proteins that are subjected to mechanical forces. Proteins providing mechanical support to the structure of the cell, such as keratin, are subjected to mechanical force, whereas proteins involved in cell movement and transport of molecules across cell membranes, such as an ion pump, are examples of generating mechanical force. 
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