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Updated: Jul 4, 2025

The Unpredictable Chronic Mild Stress Protocol for Inducing Anhedonia in Mice
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ストレス感受性およびうつ病における循環する骨髄系由来MMP8

Flurin Cathomas1,2, Hsiao-Yun Lin3,4, Kenny L Chan3,4

  • 1Nash Family Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA. Flurin.Cathomas@mssm.edu.

Nature
|February 7, 2024
PubMed
まとめ

MDD患者とマウスの場合,心理的ストレスはマトリックス金属タンパク質酶8 (MMP8) を増加させる. この免疫因子は脳の機能や 社会的行動に影響し ストレス障害の新たな治療標的となるのです

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