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Updated: Jul 3, 2025

A Direct, Regioselective and Atom-Economical Synthesis of 3-Aroyl-N-hydroxy-5-nitroindoles by Cycloaddition of 4-Nitronitrosobenzene with Alkynones
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A Direct, Regioselective and Atom-Economical Synthesis of 3-Aroyl-N-hydroxy-5-nitroindoles by Cycloaddition of 4-Nitronitrosobenzene with Alkynones

Published on: January 21, 2020

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Pd-Catalyzed Asymmetric Larock Indole Synthesis to Access Axially Chiral N -

Genwei Zhang1, Bin Yang1, Junfeng Yang1,2

  • 1Department of Chemistry, Fudan University, 2005 Songhu Road, Shanghai 200438, China.

Journal of the American Chemical Society
|February 13, 2024
PubMed
まとめ

この研究は,最初の非対称なラロックインドール合成を導入し,新しいパラジウム-ミング-フォス触媒を使用してキラルなN-アリリンドールを生成します. この方法は,高エナチオ選択性を持つ多様な軸性キラルなN-アリンドールを効率的に生成します.

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