関連する実験動画

Updated: Jul 2, 2025

RNA Interference in Aquatic Beetles as a Powerful Tool for Manipulating Gene Expression at Specific Developmental Time Points
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RNA Interference in Aquatic Beetles as a Powerful Tool for Manipulating Gene Expression at Specific Developmental Time Points

Published on: May 29, 2020

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効率的なRNA干渉ツールとしての化学的に交絡されたハンマーヘッドリボ酵素

Liang-Liang Wang1,2, Chao-Qun Wu1, Qiu-Long Zhang1,3

  • 1MOE Key Laboratory of Bioinorganic and Synthetic Chemistry, School of Chemistry, Sun Yat-Sen University, Guangzhou 510275, China.

Journal of the American Chemical Society
|February 27, 2024
PubMed
まとめ

化学的に改変されたハンマーヘッドリボ酵素 (HHRs) は,RNAのみの単純な遺伝子操作ツールを提供します. この新しいクロスリンクされたHHRは,外因性RNAと内因性RNAの両方を効率的に静止し,siRNAに匹敵する性能を持っています.

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