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Updated: Jul 1, 2025

A Direct, Regioselective and Atom-Economical Synthesis of 3-Aroyl-N-hydroxy-5-nitroindoles by Cycloaddition of 4-Nitronitrosobenzene with Alkynones
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A Direct, Regioselective and Atom-Economical Synthesis of 3-Aroyl-N-hydroxy-5-nitroindoles by Cycloaddition of 4-Nitronitrosobenzene with Alkynones

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統合された戦略により,構造的に多様なインドールアルカロイドの集合合成が可能

Jian Ren1, Shi-Hua Ding1, Xiao-Nian Li1

  • 1State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China.

Journal of the American Chemical Society
|March 6, 2024
PubMed
まとめ

研究者らは,一般的な中間物質を用いた天然製品合成のための新しい合成戦略を開発しました. このアプローチは様々なインドルとスパイロサイクルオキシンドールアルカロイドを効率的に生成し,薬物の発見のための新しい道を提供します.

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