関連する実験動画

Updated: Jul 1, 2025

ACT1-CUP1 Assays Determine the Substrate-Specific Sensitivities of Spliceosomal Mutants in Budding Yeast
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ACT1-CUP1 Assays Determine the Substrate-Specific Sensitivities of Spliceosomal Mutants in Budding Yeast

Published on: June 30, 2022

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完全に組み立てられたヒトのマイナー・スピライソームによるU12型イントロンの関与の構造的基礎

Rui Bai1,2,3, Meng Yuan4, Pu Zhang4

  • 1Research Center for Industries of the Future, Key Zhejiang Key Laboratory of Structural Biology, School of Life Sciences, Westlake University, Xihu District, Hangzhou 310024, Zhejiang Province, China.

Science (New York, N.Y.)
|March 14, 2024
PubMed
まとめ

研究者は,冷凍電子顕微鏡を用いて,ヒトのマイナー・スピライソーム・プレ-B複合体の構造を決定した. これは,U11小核リボヌクレオプロテイン (snRNP) と特定のタンパク質がU12型イントロンスプライシングを容易にするためにどのように組み合わされるかを明らかにします.

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