関連する実験動画

Updated: Jun 30, 2025

Flow Cytometry-Based Isolation and Therapeutic Evaluation of Tumor-Infiltrating Lymphocytes in a Mouse Model of Pancreatic Cancer
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Flow Cytometry-Based Isolation and Therapeutic Evaluation of Tumor-Infiltrating Lymphocytes in a Mouse Model of Pancreatic Cancer

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この微生物代謝物は,全がんにおけるT細胞幹細胞の調節により,免疫療法の有効性を高めます

Dingjiacheng Jia1, Qiwen Wang2, Yadong Qi1

  • 1Department of Gastroenterology, Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang Province 310058, China; Institution of Gastroenterology, Zhejiang University, Hangzhou, Zhejiang Province 310058, China.

Cell
|March 15, 2024
PubMed
まとめ

腸内細菌 Lactobacillus johnsonii が がんに対する免疫反応を高めています この細菌またはその代謝産物であるインドル3プロピオン酸 (IPA) を摂取すると,T細胞の機能が向上し,様々ながんに対する免疫療法の有効性が向上します.

キーワード:
ラクトバシルス・ジョンソニーTCF-1 についてガンに対する免疫療法腸内微生物群免疫チェックポイントの封鎖インドル3プロピオニン酸先祖細胞が枯渇したCD8 ((+) T細胞トリプトファンの代謝

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