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Updated: May 6, 2026

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I型インターフェロン反応性マイクログリア 皮質の形状 発達と行動

Caroline C Escoubas1, Leah C Dorman2, Phi T Nguyen3

  • 1Departments of Psychiatry and Behavioral Sciences/Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA 94158, USA.

Cell
|March 15, 2024
PubMed
まとめ

I型インターフェロン (IFN-I) は,脳の発達中にマイクログリアを活性化し,ニューロンを吸収します. IFN-I信号の喪失は,このプロセスを阻害し,過剰なニューロンと感覚過敏を引き起こします.

キーワード:
皮質の発達マイクログリア神経免疫性ファゴサイトーシス体感覚皮質タクティルの過敏症I型インターフェロン

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