関連する実験動画

Updated: Jun 30, 2025

Demonstration of Heterologous Complexes formed by Golgi-Resident Type III Membrane Proteins using Split Luciferase Complementation Assay
05:28

Demonstration of Heterologous Complexes formed by Golgi-Resident Type III Membrane Proteins using Split Luciferase Complementation Assay

Published on: September 10, 2020

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人間のGlyT1の輸送機構と薬理学

Yiqing Wei1, Renjie Li1, Yufei Meng1

  • 1Key Laboratory of Biomacromolecules (CAS), National Laboratory of Biomacromolecules, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China; College of Life Sciences, University of Chinese Academy of Sciences, Beijing 100049, China.

Cell
|March 21, 2024
PubMed
まとめ

グライシントランスポーター1 (GlyT1) の構造的な洞察は,それがどのようにグリシンを再吸収し,抗統合失調症薬がどのように結合するかを明らかにします. これは,統合失調症のNMDARを標的とした新しい治療法の開発のための基盤を提供します.

キーワード:
ALX-5407 についてGlyT1 についてPF-03463275 についてSSR504734 について抗統合失調症薬認知障害形状の変化グリシン再吸収サブストラット認識

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Mechanisms Underlying Gut Hormone Secretion Using the Isolated Perfused Rat Small Intestine07:00

Mechanisms Underlying Gut Hormone Secretion Using the Isolated Perfused Rat Small Intestine

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