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Updated: Jun 29, 2025

Artificial RNA Polymerase II Elongation Complexes for Dissecting Co-transcriptional RNA Processing Events
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Published on: May 13, 2019

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非酵素RNAプライマー拡張中の触媒金属イオン基板調整

Ziyuan Fang1, Lydia T Pazienza2,3, Jian Zhang1

  • 1Department of Chemistry, Howard Hughes Medical Institute, The University of Chicago, Chicago, Illinois 60637, United States.

Journal of the American Chemical Society
|April 5, 2024
PubMed
まとめ

Mg2+のような二重金属イオンは,非酵素RNA複製に不可欠です. この研究では,Mg2+が特にリン酸酸素と協調し,金属触媒反応によってRNAプライマーの拡張を容易にしていることが明らかになった.

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