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Updated: Jun 29, 2025

Characterize Disease-related Mutants of RAF Family Kinases by Using a Set of Practical and Feasible Methods
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腫瘍性および野生型RAS- GTPの同時抑制ががん治療に用いられる

Matthew Holderfield1, Bianca J Lee1, Jingjing Jiang1

  • 1Revolution Medicines, Redwood City, CA, USA.

Nature
|April 8, 2024
PubMed
まとめ

新しい薬であるRMC-7977は,様々なRAS変異がんの治療に有望であることが示されています. KRAS,NRAS,HRASを含む複数のRAS変種を標的にし,治療が難しい腫瘍の可能性を提示します.

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