関連する実験動画

Updated: Jun 28, 2025

Tumor Transplantation for Assessing the Dynamics of Tumor-Infiltrating CD8+ T Cells in Mice
07:36

Tumor Transplantation for Assessing the Dynamics of Tumor-Infiltrating CD8+ T Cells in Mice

Published on: June 12, 2021

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ITPRIPL1はCD3εを結合し,T細胞の活性化を阻害し,腫瘍の免疫回避を可能にします

Shouyan Deng1, Yibo Zhang1, Huanbin Wang2

  • 1Institutes of Biomedical Sciences, Shanghai Key Laboratory of Medical Epigenetics, International Co-laboratory of Medical Epigenetics and Metabolism (Ministry of Science and Technology), Zhongshan-Xuhui Hospital, Fudan University, Shanghai 200032, China.

Cell
|April 13, 2024
PubMed
まとめ

研究者は,ITPRIPL1をT細胞活性化を抑制する新しい免疫チェックポイントとして特定しました. ITPRIPL1を抗体で標的にすることは,様々な固体腫瘍に対するがん免疫療法において有望である.

キーワード:
CD3εITPRIPL1 についてガンに対する免疫療法免疫チェックポイント免疫回避

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