関連する実験動画

Updated: Jun 28, 2025

Characterization of MLKL-mediated Plasma Membrane Rupture in Necroptosis
08:55

Characterization of MLKL-mediated Plasma Membrane Rupture in Necroptosis

Published on: August 7, 2018

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NINJ1は膜ディスクを切断して放出することで,プラズマ膜の破裂を媒介する

Liron David1, Jazlyn P Borges2, L Robert Hollingsworth1

  • 1Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, USA; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA, USA.

Cell
|April 13, 2024
PubMed
まとめ

膜タンパク質NINJ1は,細胞死亡時に血膜の破裂を引き起こすリング状の構造を形成する. ガスダーミンの毛穴とは異なり,NINJ1は膜ディスクを形成し,細胞の断片化につながります.

キーワード:
NINJ1 についてNINJ2 についてニンジュリンニンジュリン2クリオ・エム炎症ゾーム炎症リンパ細胞死プラズマ膜の破裂ピロプトーシス

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Author Spotlight: Exploring Plasma Membrane Repair Mechanisms with Innovative Thermoplasmonic Puncturing

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High-throughput Measurement of Plasma Membrane Resealing Efficiency in Mammalian Cells10:07

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