Jove
Visualize
お問い合わせ

関連する概念動画

B Cell Activation and Differentiation01:24

B Cell Activation and Differentiation

1.7K
The adaptive immune response, a sophisticated defense mechanism, relies on the activation and differentiation of B lymphocytes, or B cells. These processes enable our bodies to mount a tailored response against specific pathogens such as bacteria, free virus particles, toxins, and parasites.
When naive B cells encounter a specific antigen that can bind to the B cell receptor (BCR) on their surface, they undergo sensitization to respond to the antigen's presence. Sensitization begins with...
1.7K
Cells of the Adaptive Immune Response01:23

Cells of the Adaptive Immune Response

983
The T and B lymphocytes of the adaptive immune system develop from common lymphoid progenitor cells in the bone marrow. These progenitors give rise to precursors that eventually develop into both T and B lymphocytes. As these precursors mature, they gain the ability to detect and respond to foreign antigens in the body, a process known as immunocompetence. Additionally, these precursors acquire self-tolerance, a process that ensures they do not react to self-antigens. This intricate system...
983

こちらも読む

関連記事

共著者、ジャーナル、引用グラフによってこの研究に関連する記事。

並び替え
Same author

Mutational Profile and Pathological Features of a Case of Interleukin-10 and RGS1-Positive Spindle Cell Variant Diffuse Large B-Cell Lymphoma.

Hematology reports·2023
Same author

Correction to: Chronic lymphocytic leukaemia/small lymphocytic lymphoma and mantle cell lymphoma: from early lesions to transformation.

Virchows Archiv : an international journal of pathology·2023
Same author

Correction: Different prognostic impact of recurrent gene mutations in chronic lymphocytic leukemia depending on IGHV gene somatic hypermutation status: a study by ERIC in HARMONY.

Leukemia·2023
Same author

Advances in the Classification of Myeloid and Lymphoid Neoplasms.

Virchows Archiv : an international journal of pathology·2022
Same author

Different prognostic impact of recurrent gene mutations in chronic lymphocytic leukemia depending on IGHV gene somatic hypermutation status: a study by ERIC in HARMONY.

Leukemia·2022
Same author

Tumorigenic role of Musashi-2 in aggressive mantle cell lymphoma.

Leukemia·2022
JoVE
x logofacebook logolinkedin logoyoutube logo
JoVEについて
概要リーダーシップブログJoVEヘルプセンター
著者向け
出版プロセス編集委員会範囲と方針査読よくある質問投稿
図書館員向け
推薦の声購読アクセスリソース図書館諮問委員会よくある質問
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experimentsアーカイブ
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教員リソースセンター教員サイト
利用規約
プライバシーポリシー
ポリシー

関連する実験動画

Updated: Jun 28, 2025

Tumor Engraftment in a Xenograft Mouse Model of Human Mantle Cell Lymphoma
10:52

Tumor Engraftment in a Xenograft Mouse Model of Human Mantle Cell Lymphoma

Published on: March 30, 2018

11.1K

B細胞非ホジキンリンパ腫

Elisabeth Silkenstedt1, Gilles Salles2, Elias Campo3

  • 1Department of Medicine III, LMU Hospital, Munich, Germany.

Lancet (London, England)
|April 13, 2024
PubMed
まとめ

新しい診断法と免疫療法を含むB細胞リンパ腫の理解の進展により,患者の治療が改善されました. このレビューは,これらの多様な癌の生物学,分類,管理をカバーしています.

科学分野:

  • 血液学
  • 腫瘍学
  • 免疫学

背景:

  • B細胞リンパ腫は様々な悪性腫瘍で,どの臓器にも影響を及ぼし,臨床的な表情や経過も様々です.
  • 高所得国では 10万人に20人が罹患しています
  • 生物学,診断,治療の理解における最近の進歩は,2017年以降,患者の治療結果を改善しています.

研究 の 目的:

  • B細胞非ホジキンリンパ腫の病理学,分類,予後について概要を述べる.
  • 一般的なサブタイプに関する現在の知識と治療基準を要約します.
  • 分子背景と免疫標的治療の新たな発見を強調する.

主な方法:

  • 最近の研究の文献レビューと合成.
  • 病理生物学,分類,および予後データの分析
  • 標的治療と免疫治療を含む現在の治療方法の概要

主要な成果:

  • B細胞リンパ腫の発症を誘発する分子メカニズムの理解を深めた.
  • 新しい診断方法と標的治療法の導入
  • 免疫療法戦略の進歩,特に免疫系をターゲットにする.

さらに関連する動画

A Simple Red Blood Cell Lysis Method for the Establishment of B Lymphoblastoid Cell Lines
09:49

A Simple Red Blood Cell Lysis Method for the Establishment of B Lymphoblastoid Cell Lines

Published on: January 14, 2017

14.9K
Separation of Immune Cell Subpopulations in Peripheral Blood Samples from Children with Infectious Mononucleosis
08:44

Separation of Immune Cell Subpopulations in Peripheral Blood Samples from Children with Infectious Mononucleosis

Published on: September 7, 2022

2.4K

関連する実験動画

Last Updated: Jun 28, 2025

Tumor Engraftment in a Xenograft Mouse Model of Human Mantle Cell Lymphoma
10:52

Tumor Engraftment in a Xenograft Mouse Model of Human Mantle Cell Lymphoma

Published on: March 30, 2018

11.1K
A Simple Red Blood Cell Lysis Method for the Establishment of B Lymphoblastoid Cell Lines
09:49

A Simple Red Blood Cell Lysis Method for the Establishment of B Lymphoblastoid Cell Lines

Published on: January 14, 2017

14.9K
Separation of Immune Cell Subpopulations in Peripheral Blood Samples from Children with Infectious Mononucleosis
08:44

Separation of Immune Cell Subpopulations in Peripheral Blood Samples from Children with Infectious Mononucleosis

Published on: September 7, 2022

2.4K

結論:

  • より深い生物学的洞察と新しい治療方法により,B細胞リンパ腫の治療に顕著な進展がみられた.
  • 現在の標準治療は,高度な診断と標的型/免疫療法を統合しています.
  • 将来の研究方向は,分子背景のさらなる解読と免疫ベースの治療の精製に焦点を当てています.